The hosts have 15 points and are 14th having lost 3-1 against Leicester City on December 3, while opposition manager Gary O'Neil is under pressure himself with his Wolves side in 19th place with nine points after losing 4-0 against Everton on December 4.
Here, Sports Mole rounds up the team news for both clubs.
WEST HAM UNITED vs. WOLVERHAMPTON WANDERERS
WEST HAM UNITED
Out: Michail Antonio (car accident)
Doubtful: Danny Ings (knock), Jean-Clair Todibo (groin)
Sports Mole's predicted XI: Fabianski; Wan-Bissaka, Mavropanos, Kilman, Palmieri; Alvarez, Soler; Bowen, Soucek, Kudus; Fullkrug
WOLVERHAMPTON WANDERERS
Out: Yerson Mosquera (knee), Enso Gonzalez Medina (knee), Sasa Kalajdzic (knee), Boubacar Traore (knee), Nelson Semedo (suspension)
Doubtful: Pablo Sarabia (calf)
Sports Mole's predicted XI: Bentley; Doherty, Gomes, Dawson, Ait-Nouri; Doyle, Lemina, Bellegarde; Sarabia, Cunha, Hwang
For data analysis of the most likely results, scorelines and more for this match please click here. Written by
Lewis Nolan