Carlo Ancelotti's side were confirmed as title winners earlier this month, while Villarreal sit eighth in the table, five points behind seventh-placed Real Betis, and here Sports Mole rounds up the team news.
VILLARREAL vs. REAL MADRID
VILLARREAL
Out: Kiko Femenia (suspended), Francis Coquelin (knee), Alfonso Pedraza (muscle), Gerard Moreno (muscle), Juan Foyth (foot), Denis Suarez (hamstring), Raul Albiol (muscle), Yeremy Pino (knee)
Doubtful: None
Sports Mole's predicted XI: Jorgensen; Cuenca, Bailly, Mosquera, Terrats; Traore, Comesana, Parejo, Baena; Guedes, Sorloth
REAL MADRID
Out: David Alaba (knee), Aurelien Tchouameni (foot)
Doubtful: None
Sports Mole's predicted XI: Lunin; Vazquez, Rudiger, Nacho, F Garcia; Ceballos, Camavinga, Modric; Guler; Brahim, Joselu
For data analysis of the most likely results, scorelines and more for this match please click here.