Ange Postecoglou's men were blown away 3-0 by Fulham two weekends ago, while the Hatters rescued a 1-1 draw with Nottingham Forest before the international break, and here Sports Mole rounds up the team news for the two clubs.
TOTTENHAM HOTSPUR vs. LUTON TOWN
TOTTENHAM HOTSPUR
Out: Fraser Forster (foot), Ryan Sessegnon (hamstring), Manor Solomon (knee)
Doubtful: Micky van de Ven (thigh)
Sports Mole's predicted XI: Vicario; Porro, Romero, Van de Ven, Udogie; Sarr, Bentancur; Kulusevski, Maddison, Son; Richarlison
LUTON TOWN
Out: Marvelous Nakamba (knee), Jacob Brown (knee), Tom Lockyer (heart), Joe Johnson (illness), Elijah Adebayo (thigh), Dan Potts (thigh), Amari'i Bell (thigh)
Doubtful: Alfie Doughty (hamstring), Pelly Ruddock Mpanzu (knock), Chiedozie Ogbene (unspecified), Mads Andersen (calf), Albert Sambi Lokonga (thigh), Gabriel Osho (knee)
Sports Mole's predicted XI: Kaminski; Hashioka, Mengi, Burke; Kabore, Barkley, Berry, Townsend; Chong, Clark; Morris
For data analysis of the most likely results, scorelines and more for this match please click here.