Looking to make it three straight wins at the Tottenham Hotspur Stadium, an injury-hit Gunners travelled across North London battlelines on the weekend.
Mikel Arteta's troops were without the services of Declan Rice and Martin Odegaard due to suspension and an ankle injury respectively, weakening their engine room.
Following a goalless first half, Arsenal showcased their serious threat from set pieces, with centre-back Gabriel heading in the only goal of the contest.
After the first North London derby of the season, the Gunners are sat second in the Premier League standings, whilst Spurs are languishing in 13th.
Arsenal's Jorginho makes Premier League history
Within the delight of victory at the home of a bitter rival, a Premier League record was broken by Arsenal midfielder Jorginho on Sunday afternoon.
Picking up a caution in the North London contest, the Italian received the 60th card of the top-flight weekend, breaking the previous record of 59 in a previous gameweek.
A total of 59 yellow cards were handed out over the course of a feisty Premier League weekend, as well as a single red card at St Mary's Stadium.
Chasing a lost cause, Southampton defender Jack Stephens was swiftly dismissed for a knee-high challenge on Manchester United's Alejandro Garnacho in a three-goal defeat for the hosts.
The previous record for the most cards dished out over a single set of fixtures arrived in gameweek five of last season's Premier League.
Dirtiest game in Premier League history?
Although Jorginho will possibly earn the plaudits for receiving the card that tipped the balance, Saturday night's clash at the Vitality Stadium did most of the heavy lifting in breaking the caution record.
With Bournemouth picking up six yellow cards and Chelsea collecting eight, this weekend's clash on the South Coast claimed the record for the most cards in a single Premier League match.
The contest threatened to boil over at many stages, and it was the visiting Blues who held their nerve to snatch maximum points courtesy of a late Christopher Nkunku effort.