The visitors, meanwhile, head to Sivas looking to end a barren run of form which has seen them fail to win any of their last four matches.
Match preview
Sivasspor cruised to an emphatic 3-0 victory over Sivas Dort Eylulspor in Thursday's friendly encounter at Vali Lutfullah Bilgin Tesisleri.
Bulent Uygun's men opened the scoring through Emre Gokay before second-half goals from Clinton N'Jie and Alaaddin Okumus put the result beyond doubt.
The Braves currently sit 11th in the Turkish Super Lig table and are just one point outside of a place in the top half heading into the final knockings of the season.
Awaiting them next is the challenge of an opposing outfit with little to choose between the teams over the last seven meetings which have yielded three wins apiece and one draw.
Having won four of their last five matches on home turf, Wednesday's hosts will be keen to continue their recent resurgence in front of their fans.
Fatih Karagumruk saw their winless run stretch to four matches as they played out a 1-1 draw against Besiktas at the BJK Nevzat Demir Tesisleri on Thursday.
Tolunay Kafkas's men went into the break narrowly ahead thanks to Kevin Lasagna's opener after which Rachid Ghezzal levelled matters just past the hour mark.
With just 30 points picked up from as many matches this term, the Kara Kirmizi are 18th in the standings, three points shy of safety.
Off the back of a 5-1 thrashing in their most recent away league outing, Wednesday's visitors now go in search of much-needed victory to aid their battle for survival.
Sivasspor Turkish Super Lig form:
W
D
W
D
L
L
Fatih Karagumruk Turkish Super Lig form:
W
D
D
L
L
D
Fatih Karagumruk form (all competitions):
D
D
L
L
D
D
Team News
Karagumruk's Dimitrios Kourbelis is ineligible to feature here as he serves a suspension having reached the yellow card threshold last time out.
This should see Andrea Bertolacci return to the starting XI for the first time since mid-March to pair Marcus Rohden in the heart of the midfield.
Forward Rey Manaj is expected to play some part for Sivasspor in this one after missing the defeat to Adana Demirspor due to a one-game ban.
Turkish duo Burak Kapacak and Emre Gokay are both ruled out for the visitors due to muscle injuries but the former is close to a return.
Sivasspor possible starting lineup:
Vural; Ciftci, Osmanpasa, Appindangoye, Paluli; Akdag, Caktas, Charisis; Menig, Koita, Turgunboev
Fatih Karagumruk possible starting lineup:
Sirigu; Sangare, Biraschi, Dursun, Mercan; Rohden, Bertolacci; Keles, Eysseric, Yalcin; Lasagna