The White and Blues will enter the contest off the back of a 3-2 success over Alaves, with Javi Puado scoring three times for the hosts, who are 12th in the La Liga table.
Fernando Calero and Edu Exposito remain unavailable for selection due to injury problems, but the Catalan team have not picked up any fresh issues ahead of this contest.
Gonzalez is unlikely to find a good enough reason to make changes to his side for this match, meaning that there should once again be a spot in the final third of the field for Alejo Veliz.
The 21-year-old is on loan at the club from Tottenham Hotspur, and he scored his first goal for Espanyol in their 2-1 success over Rayo Vallecano before the international break.
Walid Cheddira and Jose Gragera will be in the manager's thinking when it comes to potential alterations, but it is likely to be an unchanged XI for the clash in the Spanish capital.
Alex Kral is set to feature alongside Alvaro Aguado in the middle of midfield, while there should again be a spot in a wide area for Jofre Carreras.
Espanyol possible starting lineup: J Garcia; El Hilali, Kumbulla, Cabrera, Romero; Tejero, Kral, Aguado, Carreras; Puado, Veliz