The Reds have beaten both AC Milan and Bologna in this year's edition, while their German counterparts have fallen to one-goal defeats against Juventus and Atletico Madrid, and here Sports Mole rounds up the team news for both clubs.
RB LEIPZIG vs. LIVERPOOL
RB LEIPZIG
Out: Xaver Schlager (ACL), David Raum (ligament), Nicolas Seiwald (groin), Assan Ouedraogo (knee)
Doubtful: Lois Openda (knock), Amadou Haidara (knock)
Sports Mole's predicted XI: Gulacsi; Orban, Klostermann, Lukeba; Geertruida, Haidara, Vermeeren, Nusa; Simons; Sesko, Openda
LIVERPOOL
Out: Harvey Elliott (foot), Alisson Becker (hamstring)
Doubtful: Diogo Jota (unspecified), Conor Bradley (unspecified), Federico Chiesa (unspecified)
Sports Mole's predicted XI: Kelleher; Gomez, Konate, Van Dijk, Tsimikas; Mac Allister, Gravenberch; Salah, Jones, Diaz; Nunez
For data analysis of the most likely results, scorelines and more for this match please click here.