The 33-year-old has not been at his best in the early stages of the 2024-25 campaign, only netting once, but he managed 17 goals in Spain's top flight last season.
Budimir dropped down the bench for Osasuna's goalless draw with Valencia on Tuesday, but he is set to return to the starting XI against Barcelona, with Raul Garcia likely to be the player to drop out.
Osasuna have not reported any injury problems from their last game against Valencia, meaning that Iker Munoz and Kike Barja are set to be their only two absentees.
Budimir for Garcia is set to be one change, and there could be another in the final third of the field, with Bryan Zaragoza also in line for a recall.
Pablo Ibanez is the player pushing hardest to break into the midfield, but head coach Vicente Moreno will have been pleased with a lot of his side's work against Valencia.
There are not expected to be any surprises at the back, meanwhile, with Jorge Herrando again set to be joined by Enzo Boyomo in the middle of the defence.
Osasuna possible starting lineup: Herrera; Areso, Boyomo, Herrando, Bretones; Moncayola, Torro, M Gomez; Zaragoza, Budimir, Oroz