Adam Webster picked up a hamstring injury in the 3-2 win over Tottenham Hotspur prior to the international break and has joined James Milner (hamstring), Joao Pedro and Matt O'Riley (both ankle) in the treatment room.
South American duo Julio Enciso and Pervis Estupinan are both doubtful after returning late from international duty, but Fabian Hurzeler has confirmed that Jan Paul van Hecke is available for selection after missing the last two games with a groin problem.
Carlos Baleba could also be fit to feature despite being stretchered off in Cameroon's win over Kenya last week; the midfielder's national team manager stated after the match that he only sustained a "light injury".
A back four of Joel Veltman, Van Hecke, Lewis Dunk and Ferdi Kadioglu could line up in front of goalkeeper Bart Verbruggen, while Baleba, Jack Hinshelwood, Mats Wieffer and Yasin Ayari are all set to battle for starts in centre-midfield.
Brajan Gruda made his Premier League debut against Spurs as a late substitute, and he may begin on the bench once again this weekend as Yankuba Minteh, Georginio Rutter and Kaoru Mitoma are the most likely trio to start in the final third along with central striker Danny Welbeck.
Brighton & Hove Albion possible starting lineup: Verbruggen; Veltman, Van Hecke, Dunk, Kadioglu; Hinshelwood, Wieffer; Minteh, Rutter, Mitoma; Welbeck
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