Both teams progressed from the FA Cup third round last weekend, with the Red Devils edging past Arsenal on penalties and the Saints beating Swansea City 3-0, and here, Sports Mole rounds up all of the latest team news for the two clubs.
MANCHESTER UNITED vs. SOUTHAMPTON
MANCHESTER UNITED
Out: Diogo Dalot (suspended), Luke Shaw (calf), Mason Mount (thigh), Victor Lindelof (unspecified), Jonny Evans (unspecified)
Doubtful: Marcus Rashford (other)
Sports Mole's predicted XI: Onana; De Ligt, Maguire, Martinez; Mazraoui, Ugarte, Mainoo, Malacia; Diallo, Fernandes; Hojlund
SOUTHAMPTON
Out: Jack Stephens (unspecified), Juan Larios (unspecified), Ross Stewart (hamstring)
Doubtful: Flynn Downes (thigh)
Sports Mole's predicted XI: Ramsdale; Harwood-Bellis, Bednarek, Wood; Bree, Ugochukwu, Fernandes, Walker-Peters; Dibling, Archer, Sulemana
For data analysis of the most likely results, scorelines and more for this match please click here. Written by
Oliver Thomas