The Red Devils extended their unbeaten run in the Europa League to eight matches with success at FCSB on Thursday, whereas the Eagles were last in action a week ago against Brentford, losing 2-1 to the Bees at Selhurst Park.
Here, Sports Mole rounds up the injury and suspension news ahead of Sunday's all-important Premier League battle at the Theatre of Dreams.
MANCHESTER UNITED vs. CRYSTAL PALACE
MANCHESTER UNITED
Out: Luke Shaw (hamstring), Mason Mount (unspecified), Jonny Evans (muscle)
Doubtful: None
Sports Mole's predicted XI: Onana; De Ligt, Maguire, Martinez; Dalot, Ugarte, Fernandes, Mazraoui; Diallo, Mainoo; Zirkzee
CRYSTAL PALACE
Out: Adam Wharton (groin), Matheus Franca (rib), Cheick Doucoure (knee), Chadi Riad (knee), Joel Ward (calf)
Doubtful: None
Sports Mole's predicted XI: Henderson; Richards, Lacroix, Guehi; Munoz, Hughes, Lerma, Mitchell; Esse, Eze; Mateta
For data analysis of the most likely results, scorelines and more for this match please click here. Written by
Carter White