The Citizens come into this match following a quarter-final victory over Bournemouth in the FA Cup on the weekend, whereas the Foxes are set to make their return to the field for the first time since the international break.
Here, Sports Mole rounds up all of the latest injury and suspension news for both Man City and Leicester ahead of Wednesday night's meeting in Manchester.
MANCHESTER CITY vs. LEICESTER CITY
MANCHESTER CITY
Out: Rodri (knee), Nathan Ake (foot), John Stones (thigh), Manuel Akanji (groin)
Doubtful: Oscar Bobb (leg/fitness), Erling Haaland (knee)
Sports Mole's predicted XI: Ederson; Nunes, Gvardiol, Dias, O'Reilly; Gonzalez, Gundogan, Savinho, De Bruyne, Doku; Marmoush
LEICESTER CITY
Out: Abdul Fatawu (knee)
Doubtful: Ricardo Pereira (muscle)
Sports Mole's predicted XI: Hermansen; Faes, Coady, Okoli; Justin, Ndidi, Winks, Kristiansen; Buonanotte, El Khannous, Vardy
For data analysis of the most likely results, scorelines and more for this match please click here. Written by
Carter White