The Spain international made his return from an ankle injury off the bench against Las Palmas on Saturday, as Hansi Flick's side suffered a shocking 2-1 home defeat.
There will be changes to the starting XI for this match, with Yamal set to return alongside Dani OImo, who was an unused substitute last time out; Marc Casado is also available again after a suspension and will feature in central midfield.
Ansu Fati, Marc Bernal, Andreas Christensen, Ronald Araujo and Marc-Andre ter Stegen remain unavailable for selection through injury, while Alejandro Balde is a doubt after being withdrawn against Las Palmas due to a neck injury.
Balde has allegedly mostly recovered from the issue, which occurred during a collision with Sandro Ramirez, but he may not start here, with Gerard Martin potentially coming into the side.
Gavi, Fermin Lopez and Pablo Torre are likely to drop out of the side following the weekend defeat, but Barcelona cannot afford to rest key attacking duo Robert Lewandowski and Raphinha on Tuesday night.
Frenkie de Jong is another option in midfield, but it seems like that Casado will be given the nod alongside Pedri in the engine room.
Barcelona possible starting lineup: Pena; Kounde, Cubarsi, I Martinez, Martin; Casado, Pedri; Yamal, Olmo, Raphinha; Lewandowski
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