Arne Slot's side lead the way at the summit of the UCL standings with a perfect 12 points, while their Spanish counterparts have won just two of their opening four games to languish in 18th, and here Sports Mole rounds up the team news for both clubs.
LIVERPOOL vs. REAL MADRID
LIVERPOOL
Out: Alisson Becker (hamstring), Diogo Jota (abdominal), Federico Chiesa (fitness), Kostas Tsimikas (ankle)
Doubtful: Trent Alexander-Arnold (hamstring)
Sports Mole's predicted XI: Kelleher; Bradley, Konate, Van Dijk, Robertson; Gravenberch, Mac Allister; Salah, Szoboszlai, Diaz; Nunez
REAL MADRID
Out: Aurelien Tchouameni (ankle), Vinicius Junior (hamstring), Rodrygo (muscle), David Alaba (knee), Dani Carvajal (knee), Eder Militao (knee)
Doubtful: Lucas Vazquez (muscle)
Sports Mole's predicted XI: Courtois; Valverde, Asencio, Rudiger, Mendy; Camavinga, Modric; Guler, Bellingham, Diaz; Mbappe
For data analysis of the most likely results, scorelines and more for this match please click here.