Arne Slot's men came, saw and conquered at the Etihad Stadium on Sunday evening, slaying current champions Manchester City 2-0 thanks to Dominik Szoboszlai and Mohamed Salah's first-half strikes.
Courtesy of their win and Arsenal slipping up at home to West Ham United, the Reds' lead at the top of the table has stretched into the double figures, although a striker-starved Gunners side do have a game in hand.
Here, Sports Mole rounds up Liverpool's latest injury and suspension news ahead of the clash with Newcastle, who held off a late Nottingham Forest fightback to triumph 4-3 in Sunday's spectacular contest.
Conor Bradley
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
After Slot claimed that there was a "99.9%" chance that Conor Bradley would not face Man City, the right-back was unsurprisingly unavailable due to the hamstring injury he suffered against Aston Villa last week, and he is almost guaranteed to miss Wednesday's game too.
Joe Gomez
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Fellow defender and hamstring victim Joe Gomez has now undergone surgery on the injury he picked up in Liverpool's FA Cup fourth-round loss to Plymouth Argyle, and the Englishman is fighting an uphill battle to return before the end of the season.
Tyler Morton
Status: Out
Type of injury: Shoulder
Possible return date: Unknown
Tyler Morton is facing a few more weeks out with the shoulder injury he recently sustained, although he is only on the fringes of Slot's first team anyway.
LIVERPOOL SUSPENSION LIST
Liverpool have no players suspended for this match.
Written by
Ben Knapton