The Toffees are still hunting for their first win of the top-flight season and are reeling from a painful penalty shootout exit to Southampton in the third round of the EFL Cup in midweek.
Seamus Coleman (calf), James Garner (illness), Idrissa Gueye (personal), Nathan Patterson (thigh), Chermiti (ankle), Jarrad Branthwaite (groin) and Armando Broja (calf) were all missing from that game, and none will return in time for Saturday.
However, Dyche is hopeful that Dominic Calvert-Lewin and Vitaliy Mykolenko are both ready to play following their own illnesses, while James Tarkowski and Michael Keane should also overcome knocks to feature.
Calvert-Lewin should act as the focal point of an attack also comprising Jack Harrison, Iliman Ndiaye and Dwight McNeil, as Abdoulaye Doucoure drops back to partner Tim Iroegbunam in midfield.
Keane and Tarkowski ought to link arms defensively if passed fit, while Ashley Young - despite missing the crucial spot kick on Tuesday - and a virus-free Mykolenko would be defensive shoo-ins too.
Jordan Pickford's shaky start to the season has led to questions surrounding a possible replacement being signed - Nick Pope's name has been floated about - but England's number one is sure to guard the posts here.
Everton possible starting lineup:
Pickford; Young, Tarkowski, Keane, Mykolenko; Doucoure, Iroegbunam; Harrison, Ndiaye, McNeil; Calvert-Lewin
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