The home team's safety in the league is already confirmed, while the visitors are guaranteed to finish in the relegation playoff spot as they currently sit seven points behind Lausanne Sport in the relegation round standings.
Match preview
After the first 33 matches, the Swiss Super League table was split into a championship round for the top six and a relegation round for the bottom six clubs.
Lausanne, promoted for the 2023-24 season, secured a respectable eighth place with 40 points after the first 33 fixtures. However, they were placed in the relegation round for the rest of the season.
The Blue and White held a significant 10-point lead over 11th-placed Grasshoppers, who occupied the relegation playoff spot, going into the final five matches.
A run of three games without a win threatened Ludovic Magnin's men, but a much-needed 4-0 victory over bottom club Stade Lausanne-Ouchy secured their safety with a seven-point lead heading into the final day.
With safety secured, Lausanne will now be looking to finish third in the relegation round, as they are only two points behind Yverdon Sport.
Grasshopper, on the other hand, have endured a poor campaign. Marco Schallibaum's side finished seventh last season but have only managed 30 points from their first 33 games this time around, landing them in the relegation playoff zone.
The visitors attempted to close the ten-point gap after the league split, recording two wins and a draw to cut the deficit to four points with two games remaining.
However, their hopes of avoiding the relegation playoff were dashed after a 1-0 defeat to Basel in their last league outing.
With only pride at stake in their final match of the season, Grasshoppers will hope to end the campaign on a positive note as they prepare for the crucial relegation playoff that will determine their top-flight status.
Lausanne Sport Swiss Super League form:
W
L
L
D
L
W
Grasshopper Zurich Swiss Super League form:
L
L
W
D
W
L
Team News
Lausanne will be without defender Noe Dussenne who remains suspended after picking up a red card against Luzern.
English midfielder Trae Coyle is out of the season as he is recovering from an injury to his anterior cruciate ligament.
Grasshoppers will be without Bradley Fink who is suspended due to a red card he received against Stade Lausanne-Ouchy.
Meritan Shabani and Michael Kempter are both out of the season due to anterior cruciate ligament injuries.
Twenty-year-old midfielder Dijon Kameri is also sidelined with a muscle injury until later this month.
Lausanne Sport possible starting lineup:
Letica; Giger, Dabanli, Nanizayamo, Poaty; Custodio; Diabate, Bernede, Sanches, Kalu; Sene
Grasshopper Zurich possible starting lineup:
Hammel; Abels, Paskotsi, Seko, Matam; Tobers, Ndenge; Momoh, Morandi, Mabil; Abubakar-Ankra