Both Hojlund and Mount have recovered from injury to take part in first-team training this week and Ten Hag has revealed that he will "have to decide" whether they are fit to feature from the off or begin the contest as substitutes.
Four players who will not be involved this weekend are Victor Lindelof (toe), Tyrell Malacia (knee), Luke Shaw (calf) and Leny Yoro (foot) as they all continue to recover from injury.
Ten Hag made a total of eight changes to his side for Tuesday's thumping 7-0 home victory over Barnsley in the EFL Cup third round and the Dutchman is expected to revert to a similar side that beat Southampton 3-0 in the Premier League last weekend.
While Andre Onana is set to replace Altay Bayindir between the sticks, Diogo Dalot could be joined in the back four by Matthijs de Ligt, Lisandro Martinez and Noussair Mazraoui.
Christian Eriksen, Marcus Rashford and Alejandro Garnacho scored two goals each in the win over Barnsley and are in contention to retain their starting spots, although the latter will likely be replaced by Kobbie Mainoo, who will hope to start in midfield alongside summer signing Manuel Ugarte.
Both Rashford and Garnacho could occupy the flanks ahead of Antony and Amad Diallo, while Bruno Fernandes is poised to start in the number 10 role behind central striker Joshua Zirkzee, who will likely get the nod to start ahead of Hojlund, despite the Dane's return to training.
Manchester United possible starting lineup: Onana; Mazraoui, De Ligt, Martinez, Dalot; Ugarte, Mainoo; Garnacho, Fernandes, Rashford; Zirkzee