The Blues are already on the brink of progressing through to the last four having secured a 3-0 win from the opening fixture last week.
Since then, though, Enzo Maresca has witnessed his side be held to a 2-2 draw by Ipswich Town in the Premier League, a result that has left the club down in sixth position in the standings.
Here, Sports Mole rounds up Chelsea's injury and suspension news ahead of welcoming the Polish giants to West London.
Wesley Fofana
Status: Out
Type of injury: Thigh
Possible return date: Next season
Enzo Maresca has confirmed that Wesley Fofana will be sidelined for the remainder of the season owing to his latest fitness problem, this time another hamstring injury.
Romeo Lavia
Status: Out
Type of injury: Muscle
Possible return date: April 20 (vs. Fulham)
While Maresca has hinted that Romeo Lavia could soon be available again after his most recent injury issue, the Belgium international is ineligible for this contest.
Omari Kellyman
Status: Out
Type of injury: Hamstring
Possible return date: Next season
Omari Kellyman took to his social media accounts on March 18 to confirm that he has suffered a season-ending hamstring injury, with Chelsea looking to reintroduce the youngster into the first-team thinking next campaign.
Marc Guiu
Status: Major doubt
Type of injury: Hamstring
Possible return date: April 17 (vs. Legia Warsaw)
Last featuring for Chelsea on February 3, Marc Guiu is said to have been cleared to return to training. As it stands, Maresca may consider the Spaniard for a place on the substitutes' bench.
CHELSEA'S SUSPENSION LIST
Mykhaylo Mudryk
Mykhaylo Mudryk remains suspended after a routine urine test from the attacker contained traces of banned substances.
Written by
Darren Plant