Meanwhile, the visitors have already secured their place at next year's tournament in Morocco having won all four qualifying matches so far, and mathematically cannot finish below second place.
Match preview
Cape Verde were shocked by Botswana last month, losing 1-0 on aggregate across both legs of their AFCON qualifying double-header, sending them back down to earth after the win over Mauritania in their second match.
The Blue Sharks lost to Egypt in their opening game, leaving them with three defeats from four matches and in third place, only ahead of bottom-placed Mauritania due to a superior goal difference.
Bubista's men will now have to win their last two matches against Egypt and Mauritania if they want to have any chance of reaching the AFCON for a third consecutive edition.
Cape Verde head into Friday's clash on a run of five defeats in their last seven matches across all competitions, including a 3-0 loss against Egypt in September.
Just like last month, Liverpool forward Mohamed Salah has requested not to be involved in Egypt's qualifying matches for this month, and his wish has been granted by manager Hossam Hassan.
The decision is quite understandable as the Pharaohs are one of the seven teams that have already clinched their ticket to the 2025 AFCON in Morocco.
Having finished as runners-up in two of the last four editions of the competition, Egypt will hope to carry this form into the main tournament in a quest to end a 14-year wait for another AFCON title.
Hassan's side have won their last four games, scoring 10 goals and keeping four clean sheets in those matches, making them one of three sides alongside Nigeria and Congo DR that are yet to concede in the AFCON qualifiers.
Egypt have also won their last eight AFCON qualifiers, and in fact, have won 16, drawn four, and lost just one of their last 20 qualification matches.
Cape Verde Africa Cup of Nations Qualifying form:
L
W
L
L
Cape Verde form (all competitions):
L
W
L
W
L
L
Egypt Africa Cup of Nations Qualifying form:
W
W
W
W
Egypt form (all competitions):
W
D
W
W
W
W
Team News
Ryan Mendes has scored both of Cape Verde's goals in the AFCON qualifying so far, and he will be looking to regain his starting spot for this match.
Gilson Tavares and Gent striker Helio Varela will also hope to force their way back into the side, but former Manchester United forward Bebe and Dailon Livramento will be hoping to retain their places.
For Egypt, Salah has been omitted from the squad at his own request, leaving in-form Frankfurt striker Omar Marmoush to lead the line, while Mohamed Abdelmonem is injured, as is Zamalek star Ahmed Sayed Zizo.
Al Ahly's trio of Rami Rabia, Yasser Ibrahim, and Mohamed Hany, and Al Masry defender Khaled Sobhi, are also sidelined with injuries, while Mohamed Rabia has been called up for the first time.
Cape Verde possible starting lineup:
B Varela; Pina, Costa, Lopes; Monteiro, Duarte, Lenini; Mendes, Tavares, H Varela
Egypt possible starting lineup:
El-Shenawy; Eid, Abdelmaguid, Ramadan, Hamdi; Attia, Fathi; Fathy, Zizo, Adel; Marmoush