Josh Dasilva, Rico Henry (both knee) and Aaron Hickey (thigh) all remain long-term absentees as they continue to recover from injury, while Kristoffer Ajer (foot) and Gustavo Nunes (back) are both doubtful and will be assessed ahead of kickoff.
Christian Norgaard was shown a straight red card in Brentford's 0-0 draw with Everton last weekend, but the midfielder is available for selection following a successful appeal.
The Dane is therefore set to continue in the middle of the pitch along with Vitaly Yanelt and Mathias Jensen, with Yehor Yarmolyuk providing cover on the substitutes' bench.
Thomas Frank will likely stick with a four-man defence which could see Keane Lewis-Potter continue at left-back next to Ethan Pinnock, Nathan Collins and Sepp van den Berg.
Igor Thiago made his long-awaited debut for Brentford as a substitute against Everton and the summer signing from Club Brugge is in contention to feature again this weekend, although a start seems unlikely, so Bryan Mbeumo, Yoane Wissa and Mikkel Damsgaard should all continue in attack.
Brentford possible starting lineup: Flekken; Van den Berg, Collins, Pinnock, Lewis-Potter; Jensen, Norgaard, Janelt; Mbeumo, Wissa, Damsgaard