The 29-year-old made his debut for the Cherries in their gripping 3-2 win over Everton two weekends ago, where they set a new record for the latest a team has ever come back from two goals down to prevail in a Premier League fixture.
However, Kepa is ineligible to face his parent club this weekend, and with Neto joining Arsenal on loan on deadline day, Bournemouth will have to call upon Mark Travers to guard the posts.
The 25-year-old should be shielded by Julian Araujo, Milos Kerkez and Ilya Zabarnyi in a youthful backline, while Dean Huijsen can feel hopeful of replacing Marcos Senesi in the other centre-back spot.
Tyler Adams and Philip Billing are both on the mend from back problems, but there could be an alteration in midfield either way, as Alex Scott bids to displace Ryan Christie to start next to Lewis Cook.
Justin Kluivert ought to pull the strings in the number 10 slot just ahead of Scott and Cook, but Iraola is faced with a quandary in the final third following Luis Sinisterra's game-changing performance at Goodison Park, where he both scored and laid on an assist in that dramatic comeback.
Sinisterra has surely played his way into a start alongside Kluivert and Antoine Semenyo, meaning that one of Evanilson and Marcus Tavernier should be axed from the XI; the latter will likely be sacrificed and join injury victim Enes Unal (foot) on the sidelines.
Bournemouth possible starting lineup:
Travers; Araujo, Zabarnyi, Huijsen, Kerkez; Scott, Cook; Semenyo, Kluivert, Sinisterra; Evanilson