Hansi Flick's side maintained their 100% record in the league with a statement 5-1 victory over Villarreal at the Estadio de la Ceramica, where Robert Lewandowski and Raphinha registered braces alongside Pablo Torre's first La Liga goal.
While the league leaders will be targeting a seventh successive victory in the top flight, Getafe are still searching for their first win of the season after drawing four and losing two of their six matches.
Here, Sports Mole takes an in-depth look at the head-to-head record and previous meetings between the two sides.
Head-to-head record
Previous meetings: 44
Barcelona wins: 30
Draws: 10
Getafe wins: 4
Barcelona have made a habit of picking up wins against Getafe, having won 75% of their previous 44 head-to-head meetings.
The Blaugrana have amassed 102 goals in their previous encounters with the Azulones, while the Madrid-based team have found the net on 33 occasions.
Barcelona legend Lionel Messi holds the honour of being the all-time leading scorer in this fixture after scoring 21 goals in his 27 matches against Getafe.
The Catalan giants are currently enjoying a seven-game unbeaten run against the Azulones, including a 4-0 win when the two sides last met in February.
On that occasion, Raphinha, Joao Felix, Frenkie de Jong and Fermin Lopez all got on the scoresheet to fire the Blaugrana to a dominant 4-0 win at the Estadi Olimpic Lluis Companys.
The Blaugrana have experienced frustration in their recent away meetings, having failed to win on any of their last four trips to the Coliseum.
Getafe began that run of results with a 1-0 victory in October 2020, before holding Barcelona to goalless draws in their previous three matches.
With that in mind, the Blaugrana will be relieved to have home advantage for Wednesday's fixture, especially as they won each of their previous six head-to-head matches in front of their own supporters.
In fact, Barcelona have never lost a competitive home game against Getafe, having won 18 and drawn four of their 22 home encounters.
The last time Barcelona failed to win a home game against Getafe was in February 2018 when Ernesto Valverde's side was held to a goalless draw at the Camp Nou.
Meanwhile, Getafe have gone five head-to-head matches without troubling the scorers since Sandro Ramirez found the net in a 2-1 away defeat in August 2021.
Last 20 meetings
Feb 24, 2024: Barcelona 4-0 Getafe (La Liga)
Aug 13, 2023: Getafe 0-0 Barcelona (La Liga)
Apr 16, 2023: Getafe 0-0 Barcelona (La Liga)
Jan 22, 2023: Barcelona 1-0 Getafe (La Liga)
May 15, 2022: Getafe 0-0 Barcelona (La Liga)
Aug 29, 2021: Barcelona 2-1 Getafe (La Liga)
Apr 22, 2021: Barcelona 5-2 Getafe (La Liga)
Oct 17, 2020: Getafe 1-0 Barcelona (La Liga)
Feb 15, 2020: Barcelona 2-1 Getafe (La Liga)
Sep 28, 2019: Getafe 0-2 Barcelona (La Liga)
May 12, 2019: Barcelona 2-0 Getafe (La Liga)
Jan 06, 2019: Getafe 1-2 Barcelona (La Liga)
Feb 11, 2018: Barcelona 0-0 Getafe (La Liga)
Sep 16, 2017: Getafe 1-2 Barcelona (La Liga)
Mar 12, 2016: Barcelona 6-0 Getafe (La Liga)
Oct 31, 2015: Getafe 0-2 Barcelona (La Liga)
Apr 28, 2015: Barcelona 6-0 Getafe (La Liga)
Dec 13, 2014: Getafe 0-0 Barcelona (La Liga)
May 03, 2014: Barcelona 2-2 Getafe (La Liga)
Jan 16, 2014: Getafe 0-2 Barcelona (Copa del Rey - Fifth Round)
Last 10 La Liga meetings
Feb 24, 2024: Barcelona 4-0 Getafe (La Liga)
Aug 13, 2023: Getafe 0-0 Barcelona (La Liga)
Apr 16, 2023: Getafe 0-0 Barcelona (La Liga)
Jan 22, 2023: Barcelona 1-0 Getafe (La Liga)
May 15, 2022: Getafe 0-0 Barcelona (La Liga)
Aug 29, 2021: Barcelona 2-1 Getafe (La Liga)
Apr 22, 2021: Barcelona 5-2 Getafe (La Liga)
Oct 17, 2020: Getafe 1-0 Barcelona (La Liga)
Feb 15, 2020: Barcelona 2-1 Getafe (La Liga)
Sep 28, 2019: Getafe 0-2 Barcelona (La Liga)
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