The home side are six points clear of second-placed Real Madrid at the summit, while Espanyol sit down in 17th position, and here Sports Mole rounds up the team news for the two sides.
BARCELONA vs. ESPANYOL
BARCELONA
Out: Ferran Torres (hamstring), Marc-Andre ter Stegen (knee), Marc Bernal (knee), Andreas Christensen (Achilles), Ronald Araujo (hamstring), Eric Garcia (muscle)
Doubtful: None
Sports Mole's predicted XI: Pena; Kounde, Cubarsi, I Martinez, Balde; De Jong, Pedri; Yamal, Olmo, Raphinha; Lewandowski
ESPANYOL
Out: Pol Lozano (muscle), Fernando Calero (muscle), Edu Exposito (knee)
Doubtful: Jose Gragera (foot)
Sports Mole's predicted XI: Garcia; El Hilali, Kumbulla, Cabrera, Olivan; Tejero, Kral, Gragera, Carreras; Puado, Veliz
For data analysis of the most likely results, scorelines and more for this match please click here.