As Argentina stopper Emiliano Martinez was forced off by a hand injury at half time of Sunday's Premier League defeat to Chelsea, his replacement Robin Olsen could be called upon to start against the Bees at Villa Park.
Amid a long winless run, boss Unai Emery might be tempted to make further changes to his lineup in midweek, with Ross Barkley, Ian Maatsen and Leon Bailey fronting the queue for promotion from the bench.
Diego Carlos is an option if Emery decides to shuffle his unsteady defence, while a struggling attack could be livened up by the introduction of super-sub Jhon Duran.
Leading goalscorer Ollie Watkins - who joined Villa from Brentford four years ago - is still favourite to start up front, despite finding the net just once in his last seven matches and missing some good chances at the weekend.
Morgan Rogers has become an integral part of Emery's plans this season, so he should keep his place behind Villa's central striker, regardless of a recent dip in form.
Martinez aside, only Jacob Ramsey and Amadou Onana are expected to miss out due to injury, though the latter could yet come through a fitness test to make the bench.
Aston Villa possible starting lineup: Olsen; Cash, Konsa, Torres, Maatsen; Barkley, Tielemans; Bailey, Rogers, McGinn; Watkins
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