The Denmark international has missed the team's opening two friendlies of the summer against Rosenborg and Rangers due to his involvement in Euro 2024, but he has made the trip to the US alongside international teammate Christian Eriksen and could start against Mikel Arteta's team.
Scott McTominay is also present despite his involvement for Scotland at the European Championship, while Harry Maguire is with the squad, as he bids to overcome a muscular issue.
New signing Leny Yoro made his debut in last weekend's 2-0 success over Rangers, and the 18-year-old is again in line to start in the middle of the defence against Arsenal.
However, fellow new arrival Joshua Zirkzee has been given extra time off due to his involvement for Netherlands at Euro 2024, so he will not feature for the club on their tour.
Tyrell Malacia remains on the sidelines through injury, while Altay Bayindir, Diogo Dalot, Bruno Fernandes, Alejandro Garnacho, Kobbie Mainoo, Lisandro Martinez, Facundo Pellistri and Luke Shaw are on breaks due to their international involvement over the summer.
Head coach Erik ten Hag has still been able to bring a strong squad to the US, though, and the likes of Andre Onana, Casemiro, Mason Mount, Amad Diallo and Marcus Rashford should be in the XI here.
Manchester United possible starting lineup: Onana; Wan-Bissaka, Yoro, Evans, Amass; Casemiro, McTominay, Mount; Amad, Hojlund, Rashford