Arne Slot's men head to North London boasting a four-point advantage over the Gunners in the standings, and they made it six wins from six away games this season with a 1-0 success over RB Leipzig in Wednesday's Champions League game.
The Gunners were also victorious by a slender margin in Europe in midweek, edging out Shakhtar Donetsk, but Mikel Arteta is dealing with some unenviable injury worries before Sunday's crunch clash.
Here, Sports Mole takes an in-depth look at the head-to-head record and previous meetings between the two sides.
Head-to-head record
Previous meetings: 242
Arsenal wins: 83
Draws: 64
Liverpool wins: 95
Over 130 years on from the first-ever meeting between Arsenal and Liverpool - a Division Two clash in 1893 that was won 5-0 by the Reds - the two English giants have crossed paths on a staggering 242 occasions in competitive action.
Unsurprisingly, neither has managed to build up a truly dominant streak over the other, although Liverpool do boast the superior wins tally with 95 compared to 83 for Arsenal, and 64 other clashes have ended with the points split.
A fixture that was dominated by Liverpool during the late days of the Arsene Wenger reign, the whole of Unai Emery's stint and the early days of Arteta's tenure, Arsenal have since turned the tables, going unbeaten in their last four Premier League games.
In the 2022-23 and 2023-24 seasons, both showdowns at the Emirates saw Arsenal prevail, and the Gunners were able to leave Anfield with a point in both of those years too, although the 2022-23 affair saw Arteta's men let a 2-0 lead slip in a 2-2 stalemate.
Liverpool have conquered their North London foes in 2024, though, ensuring that the Gunners would not be going for a 15th FA Cup title with a 2-0 third-round win in January, where Arsenal were punished for not putting away their chances.
From October 2020 to March 2022, Arteta's side also went on an embarrassing six-game run without even managing a single goal against Jurgen Klopp's Liverpool, although they did win the first of those games - an EFL Cup penalty shootout following a goalless draw.
In contrast, the Merseyside giants have to go all the way back to August 2015 for the last time that they failed to score in a Premier League game versus Arsenal, a goalless draw at the Emirates during the closing period of Brendan Rodgers's reign.
The individual scoring records also belong to Liverpool, as Robbie Fowler (12) and Roberto Firmino (11) boast the most documented goals in this head-to-head, while Mohamed Salah and Thierry Henry have nine apiece.
Last 20 meetings
Feb 04, 2024: Arsenal 3-1 Liverpool (Premier League)
Jan 07, 2024: Arsenal 0-2 Liverpool (FA Cup Third Round)
Dec 23, 2023: Liverpool 1-1 Arsenal (Premier League)
Apr 09, 2023: Liverpool 2-2 Arsenal (Premier League)
Oct 09, 2022: Arsenal 3-2 Liverpool (Premier League)
Mar 16, 2022: Arsenal 0-2 Liverpool (Premier League)
Jan 20, 2022: Arsenal 0-2 Liverpool (EFL Cup Semi-Finals)
Jan 13, 2022: Liverpool 0-0 Arsenal (EFL Cup Semi-Finals)
Nov 20, 2021: Liverpool 4-0 Arsenal (Premier League)
Apr 03, 2021: Arsenal 0-3 Liverpool (Premier League)
Oct 01, 2020: Liverpool 0-0 Arsenal (EFL Cup Fourth Round)
Sep 28, 2020: Liverpool 3-1 Arsenal (Premier League)
Aug 29, 2020: Arsenal 1-1 Liverpool (Community Shield)
Jul 15, 2020: Arsenal 2-1 Liverpool (Premier League)
Oct 30, 2019: Liverpool 5-5 Arsenal (EFL Cup Fourth Round)
Aug 24, 2019: Liverpool 3-1 Arsenal (Premier League)
Dec 29, 2018: Liverpool 5-1 Arsenal (Premier League)
Nov 03, 2018: Arsenal 1-1 Liverpool (Premier League)
Dec 22, 2017: Arsenal 3-3 Liverpool (Premier League)
Aug 27, 2017: Liverpool 4-0 Arsenal (Premier League)
Last 10 Premier League meetings
Feb 04, 2024: Arsenal 3-1 Liverpool (Premier League)
Dec 23, 2023: Liverpool 1-1 Arsenal (Premier League)
Apr 09, 2023: Liverpool 2-2 Arsenal (Premier League)
Oct 09, 2022: Arsenal 3-2 Liverpool (Premier League)
Mar 16, 2022: Arsenal 0-2 Liverpool (Premier League)
Nov 20, 2021: Liverpool 4-0 Arsenal (Premier League)
Apr 03, 2021: Arsenal 0-3 Liverpool (Premier League)
Sep 28, 2020: Liverpool 3-1 Arsenal (Premier League)
Jul 15, 2020: Arsenal 2-1 Liverpool (Premier League)
Aug 24, 2019: Liverpool 3-1 Arsenal (Premier League)
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