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With just 90 minutes of football still to be played in Group G, all four teams can still qualify. Wolfsburg currently lie bottom of the section, but will go through if they win and will even finish top of the group if Salzburg and Sevilla draw in the night's other match. Koen Casteels has missed his club's last three competitive outings, including last weekend's Bundesliga defeat at Mainz, but the Wolves' first-choice goalkeeper is expected to feature and captain the side for the encounter at the Volkswagen Arena. Nmecha's booking in the Matchday 5 loss in Seville means he is suspended leaving Luca Waldschmidt, who has only recently returned from a thigh injury, in line to make his first Champions League start for the club.
Lille also have disciplinary problems with Xeka and Jonathan Bamba both suspended following yellow cards in the 1-0 win over Salzburg that took the French champions to the top of the group last time out. Key midfielder Benjamin Andre and France international forward Jonathan Ikone both missed that game with bans, but are available. USMNT forward Timothy Weah is out, however, after suffering a thigh injury in training late last week as Jocelyn Gourvennec's side go for the win that will assure them of top spot in the group. They will also finish first if they draw and second-placed Salzburg — currently one point behind — do not win at home to Sevilla. A point will be enough for Lille to secure a place in the knockout stages.
Match stats
John Brooks was sent off in the second half as Wolfsburg drew 0-0 at Lille on Matchday 1 in September.
Nmecha is Wolfsburg's seven-goal top scorer in all competitions so far this season. He's scored twice in the Champions League.
Wout Weghorst has six goals for the campaign, but is yet to score in four Champions League appearances.
Wolfsburg have won four of their last six home European matches (D1, L1), and are unbeaten in seven Champions League fixtures at the Volkswagen-Arena (W6, D1).
The Wolves finished top of their section six years ago, collecting 12 points from a group that also included Manchester United, PSV Eindhoven and CSKA Moscow, and went on to reach the quarter-finals.
Lille have won just one of their 10 matches against German opposition (D4, L5), and are winless in five on German soil (D2, L3).
Lille's Renato Sanches made 53 competitive appearances for Bayern Munich between 2016 and 2018, winning two Bundesliga titles and the DFB Cup.
Probable line-ups
Wolfsburg: Casteels (c) - Lacroix, Guilavogui, Brooks - Baku, Vranckx, Arnold, Otavio - Lukebakio, Weghorst, Waldschmidt
Out: Mehmedi (muscular), Schlager (knee), William (knee), Nmecha (suspended)
Doubtful: Steffen (calf)
Coach: Florian Kohfeldt
Lille: Grbic - Celik, Fonte (c), Botman, Reinildo - Ikone, Sanches, Andre, Gomes (or Yazici) - David, Yilmaz
Out: Xeka (suspended), Weah (thigh), Bamba (suspended)
Doubtful: -
Coach: Jocelyn Gourvennec