United drew with West Ham in midweek while Leicester lost to Tottenham heading into the final weekend.
The top-flight rivals are battling it out for a top-four finish this term with a win for either guaranteeing Champions League football.
United only need a point to confirm their place in the top four while a draw would be enough for the Foxes too if Chelsea lose to Wolves.
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Leicester v Man United: Date and kick-off time
The Premier League match will be held at the King Power on Sunday, July 26 and will kick-off at 4pm.
United beat Leicester 1-0 at Old Trafford in September thanks to Marcus Rashford's penalty.
The Red Devils also won 1-0 on their last visit to East Midlands with Rashford again netting the winner.
The Foxes have not beaten their rivals since September 2014 when they claimed a thrilling 5-3 home victory.
Leicester v Man United: TV channel and live stream
The game is being broadcast on Sky Sports Main Event from 3pm.
Sky Sports customers can live stream this via the app using their mobile, tablet or computer devices.
If not, you can purchase a Sky Sports Day Pass from NowTV for £8.99.
Leicester v Man United: Radio coverage
talkSPORT will have full, exclusive coverage of the match with kick-off set for 4pm.
Fans will have the option to listen to the game with or without crowd noise, so you can choose whichever way suits you best.
Adrian Durham will be your host while Sam Matterface and Stuart Pearce will be on commentary duty - to listen in click on one of the radio players below.
Listen to talkSPORT commentary with crowd noise
Listen to talkSPORT commentary without crowd noise (available from kick-off time)
Leicester and Manchester United face off on the last day of the 2019/20 Premier League season.