Go Ahead Eagles vs. PSV (Wednesday, 5.45pm)
PSV Eindhoven travel to De Adelaarshorst on Wednesday for their meeting against Go Ahead Eagles seeking to bounce back from their first league defeat of the season last time out.
Meanwhile, the home side go in search of a third consecutive win on home turf where they have been a real force to reckon with since their promotion.
We say: Go Ahead Eagles 0-4 PSV Eindhoven
PSV will be expected to give an immediate response to last week's loss as they make the journey to a venue where visiting teams have not had much joy this term. Nonetheless, we fancy the away side to come out on top in a comfortable manner, grabbing plenty of goals en route.
NEC vs. Utrecht (Wednesday, 5.45pm)
Seeking to return to winning ways after dropping points in their respective outings last time out, NEC and FC Utrecht face off at Stadion de Goffert on Wednesday.
With only goal difference separating the sides after the first five rounds of matches, the contest has all the makings of an absorbing affair.
We say: NEC 1-2 FC Utrecht
NEC have punched considerably above their weight since their return to the top flight and have every reason to be confident of another positive result in this one. However, we are backing a more experienced Utrecht side to claim the victory here, albeit only by a narrow margin.
Groningen vs. Vitesse (Wednesday, 7.00pm)
Aiming to bounce back from respective defeats last time out, Groningen and Vitesse face off at the Hitachi Capital Mobility Stadium on Wednesday.
The sides are separated by just one point in the Eredivisie table, so both teams have all to play for ahead of this one which should give rise to an absorbing contest.
We say: Groningen 1-1 Vitesse
The teams are on a rough patch at the moment but both of them will sense an opportunity to get going by securing all three points against fellow strugglers. We expect an open and exciting game with a share of the spoils come the full-time whistle.
Feyenoord vs. Heerenveen (Wednesday, 8.00pm)
Off the back of victories in their respective last outings, Feyenoord and Heerenveen lock horns at De Kuip in matchday six of the 2021-22 Eredivisie season.
The sides have made positive starts to the new campaign with the visitors in third place, one point and two places above the hosts who have played a game less.
We say: Feyenoord 2-1 Heerenveen
Both sides have a real chance of coming away with all three points in a game that could easily swing either way. However, we fancy the home side to carry the day but only after they have been pushed all the way by their visitors.
PEC Zwolle vs. Sparta (Wednesday, 8.00pm)
PEC Zwolle play host to Sparta Rotterdam on Wednesday evening, still searching for their first point of the new Eredivisie season.
Sparta have also endured an indifferent opening to the campaign, collecting just five points from as many fixtures.
We say: PEC Zwolle 1-2 Sparta Rotterdam
We feel that Wednesday evening could be the time where Zwolle finally get on the scoresheet. However, Sparta appear to be trending upwardly, and that is enough for us to predict an away win for the visitors by the odd goal in three.