Spurs returned to winning ways last time out after edging a 2-1 win against Brighton in a fiery affair which saw managers Cristian Stellini and Roberto De Zerbi both sent off.
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Tottenham benefitted from a VAR error which saw the Seagulls have two goals ruled out to stretch their unbeaten run to four games.
The north Londoners now welcome a second side from the south coast, with Bournemouth moving three points clear of the relegation zone following a 1-0 victory over Leicester.
But Tottenham are in as equal need for a win as the Cherries, languishing three behind fourth-placed Manchester United.
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Tottenham vs Bournemouth: talkSPORT coverage
This Premier League clash is set to take place on Saturday, April 15.
Kick-off at the Tottenham Hotspur Stadium is scheduled for 3pm.
talkSPORT 2 will have live and EXCLUSIVE coverage from London, with this game not available to watch on UK TV.
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Dan Windle will serve as your presenter, while commentary will then come from Joe Shennan and former Arsenal winger Perry Groves.
To tune in to talkSPORT or talkSPORT 2 through the website, click HERE for the live stream.
You can also listen via the talkSPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM.
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Tottenham vs Bournemouth: Team news
The hosts have a number of players absent through injury, with Rodrigo Bentancur, Emerson Royal, Ryan Sessegnon, Ben Davies and Yves Bissouma all out.
Lucas Moura is serving the second of a three-game suspension with Richarlison hoping to force himself into the starting eleven.
Bournemouth have several injuries of their own with Ryan Fredericks and Junior Stanislas both unavailable.
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Cherries boss Gary O'Neil is more hopeful on the fitness of Marcos Senesi and Hamed Traore, who will be undergo late fitness checks.
Tottenham vs Bournemouth: What has been said?
Gabby Agbonlahor believes that Vincent Kompany should stay at Burnley following links with the vacant managerial role at Spurs.
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Speaking on talkSPORT Breakfast, he said: "I can see why they're looking at Kompany, but if i was Kompany I would say no. Capital letters, NO.
"He's got Burnley into the Premier League, give it a go with Burnley and even if he didn't keep Burnley up, what he done with them in the Championship is still going to attract Premier League jobs.
"The way Spurs are at the moment as a club, why would you touch that? Why would you leave Burnley… he could, in the summer, bring in the right players and have a good go with Burnley and shock the Premier League.
"You know like Sheffield United did, Leeds did? He could do that with Burnley."
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Tottenham vs Bournemouth: Match facts
Philip Billing's seven Premier League goals have been worth nine points to Bournemouth this season - only Josh King in 2016-17 (12) has ever earned the Cherries more points thanks to his goals in a single campaign.
Harry Kane's Premier League goals have been worth 22 points to Tottenham this season, the highest of any player in the division. In Premier League history, only Gareth Bale in 2012-13 (24) and Kane himself in 2014-15 (24) have earned more points with their goals for Spurs in a single campaign.
Tottenham's Harry Kane has scored in 20 different Premier League games in 2022-23, more than any other player (Erling Haaland 18), and his most ever in a season (19 in 2017-18). Only five players have ever scored in more separate matches in a single campaign in the competition, most recently Mo Salah in 2017-18 (24).
Tottenham's Son Heung-min became the first ever Asian player to score 100 Premier League goals with his strike against Brighton last time out. No player has scored more often from outside the box than the Korean this term, with three of his seven strikes so far coming from distance.
Bournemouth (304) and Tottenham (295) have had more high turnovers against them than any other side in the Premier League this season. Meanwhile, despite making fewer high turnovers than any other team (201), only Man City (9) have scored more such goals this term than Tottenham (8).
Bournemouth have won four of their last eight Premier League games (L4), as many as they had in their first 22 this season (D6 L12). Following their 1-0 win at Leicester last time out, the Cherries are looking to win back-to-back top-flight away games for the first time since October 2018.
Tottenham have won each of their last five Premier League matches at the Tottenham Hotspur Stadium, earning more home points in the competition since the start of February than any other side (15). Indeed, each of Spurs' last five league wins have come at home, their longest such spell since having a run of nine wins coming on home soil from January to September 2019.
Since a 3-1 defeat at Leeds in May 2021, Tottenham have won 10 of their last 11 Premier League games against promoted sides (D1), including all five this season. At home, Spurs have lost just one of their last 32 such games (W29 D2), going down 3-1 against Wolves in December 2018.
Bournemouth have only taken five points in 11 previous Premier League meetings with Spurs (W1 D2 L8), with their one win coming in May 2019, 1-0 at the Vitality Stadium.
Tottenham Hotspur have won all five of their home Premier League games against Bournemouth, beating them in all five campaigns between 2015-16 and 2019-20.