On matchday one, Emery opted to go with five alterations for the meeting against Legia Warsaw in Poland, that decision backfiring on the Spaniard as Villa lost by a 3-2 scoreline.
However, he has decided to take the same approach for the home showdown with Zrinjski, including handing another European start to Youri Tielemans.
Ezri Konsa appears in line to feature at right-back, allowing Diego Carlos and Clement Lenglet to play in the middle of the defence.
Leander Dendoncker comes into the midfield, while Leon Bailey and Jhon Duran are handed opportunities in the final third.
Matty Cash and Pau Torres are the players to drop out of the defence, while Boubacar Kamara and Douglas Luiz do not feature in midfield.
Ollie Watkins is selected as a replacement, but Moussa Diaby is a notable absentee from the squad through injury.
Aston Villa: Martinez; Konsa, Diego Carlos, Lenglet, Digne; McGinn, Dendoncker, Tielemans; Zaniolo, Duran, Bailey
Subs: Olsen, Marschall, Cash, Luiz, Traore, Watkins, Torres, Chambers, O'Reilly
Zrinjski Mostar: Maric; Bilbija, Canadjija, Corluka, Cuze, Hrvanovic, Ivancic, Jakovljevic, Radic, Senic, Ticinovic
Subs: Balic, Kis, Kozulj, Malekinusic, Marin, Memija, Misic, Niron, Prskalo, Sabljic, Sefo, Ziomislic
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