The Lilywhites are top of the section with seven points to their name, one clear of Ruben Amorim's side and Marseille, and here Sports Mole rounds up the team news for both clubs.
TOTTENHAM HOTSPUR vs. SPORTING LISBON
TOTTENHAM HOTSPUR
Out: Dejan Kulusevski (hamstring), Richarlison (calf)
Doubtful: Cristian Romero (calf), Pierre-Emile Hojbjerg (thigh)
Sports Mole's predicted XI: Lloris; Sanchez, Dier, Davies; Emerson, Skipp, Bentancur, Bissouma, Perisic; Kane, Son
SPORTING LISBON
Out: Ricardo Esgaio (suspended), Pedro Goncalves (suspended), Luis Neto (knee), Daniel Braganca (cruciate ligament)
Doubtful: Jeremiah St Juste (hamstring), Sebastian Coates (unspecified)
Sports Mole's predicted XI: Adan; Inacio, Marsa, Reis; Porro, Ugarte, Morita, Santos; Trincao, Edwards; Paulinho
For data analysis of the most likely results, scorelines and more for this match please click here.