The Red Devils secured a comeback 2-1 win over Brentford before the international break, while he Blades were beaten 3-1 by Fulham last time out, and here, Sports Mole rounds up all of the latest team news for the two clubs.
SHEFFIELD UNITED vs. MANCHESTER UNITED
SHEFFIELD UNITED
Out: Chris Basham (leg), John Egan (Achilles), Tom Davies (thigh), Daniel Jebbison (illness)
Doubtful: Ben Osborn (groin), Rhys Norrington-Davies (thigh), Max Lowe (ankle), George Baldock (calf), William Osula (muscle)
Sports Mole's predicted XI: Foderingham; Trusty, Ahmedhodzic, Robinson; Bogle, Norwood, Souza, Thomas; Hamer, McAtee; Archer
MANCHESTER UNITED
Out: Casemiro (unspecified), Lisandro Martinez (foot), Luke Shaw (muscle), Tyrell Malacia (knee), Aaron Wan-Bissaka (muscle), Amad Diallo (knee), Kobbie Mainoo (ankle), Jadon Sancho (disciplinary reasons)
Doubtful: None
Sports Mole's predicted XI: Onana; Dalot, Varane, Lindelof, Reguilon; Amrabat, McTominay; Fernandes, Mount, Rashford; Hojlund
For data analysis of the most likely results, scorelines and more for this match please click here.