The Catalan outfit have already been confirmed as champions but suffered a 2-1 loss to Real Sociedad on Saturday, while Real Valladolid were beaten 2-0 at Cadiz on Friday and have since dropped into the relegation zone, currently sitting 18th in the table, level on points with 17th-placed Getafe.
Here, Sports Mole rounds up the team news for the two sides ahead of the match.
REAL VALLADOLID vs. BARCELONA
REAL VALLADOLID
Out: Luis Perez (muscle), Selim Amallah (shoulder), Anuar Tuhami (ligament), Martin Hongla (suspended)
Doubtful: None
Sports Mole's predicted XI: Masip; Fernandez, Sanchez, El Yamiq; Rosa, Monchu, Aguado, Olaza; Plata, Marin, Leon
BARCELONA
Out: Pedri (muscle), Ronald Araujo (muscle), Jules Kounde (muscle)
Doubtful: None
Sports Mole's predicted XI: Ter Stegen; Roberto, Alonso, Christensen, Balde; Gavi, Busquets, F de Jong; Dembele, Lewandowski, Raphinha
For data analysis of the most likely results, scorelines and more for this match please click here.