Los Blancos were 2-0 winners over Rayo Vallecano last time out, while Atletico will enter the contest off the back of a 2-1 victory over Rayo Vallecano, and here Sports Mole rounds up the team news.
REAL MADRID vs. ATLETICO MADRID
REAL MADRID
Out: Aurelien Tchouameni (suspended), Eder Militao (knee), Thibaut Courtois (knee), David Alaba (knee)
Doubtful: Antonio Rudiger (thigh)
Sports Mole's predicted XI: Lunin; Carvajal, Rudiger, Nacho, Mendy; Valverde, Camavinga, Kroos; Bellingham; Rodrygo, Vinicius
ATLETICO MADRID
Out: Jose Gimenez (muscle), Cesar Azpilicueta (knee), Thomas Lemar (Achilles)
Doubtful: Alvaro Morata (muscle)
Sports Mole's predicted XI: Oblak; Witsel, Hermoso, Reinildo; Molina, De Paul, Koke, Saul, Lino; Griezmann, Morata
For data analysis of the most likely results, scorelines and more for this match please click here.