The striker returned after recovering from a fractured skull as Wanderers began the season with a 1-0 defeat at Leicester last weekend. The Mexico international is expected to keep his place in the starting line-up.
Defensive duo Yerson Mosquera and Willy Boly remain out with hamstring injuries, along with Pedro Neto, Jonny (both knee) and Daniel Podence (groin).
Tottenham will make a decision whether to include wantaway striker Harry Kane after Saturday's training session as Nuno Espirito Santo returns to Molineux.
Record signing Tanguy Ndombele will not be included as he continues to be frozen out by Nuno.
Cristian Romero should be OK after coming through his first 90 minutes since July in the Europa Conference League match against Pacos de Ferreira, but fellow defender Joe Rodon is injured.
Wolves provisional squad: Sa, Ruddy, Hoever, Ait-Nouri, Coady, Semedo, Saiss, Marcal, Kilman, Neves, Gibbs-White, Moutinho, Dendoncker, Silva, Traore, Jimenez, Trincao.
Tottenham provisional squad: Lloris, Gollini, Tanganga, Doherty, Sanchez, Dier, Romero, Reguilon, Davies, Sissoko, Skipp, Hojbjerg, Lo Celso, Alli, Bergwijn, Moura, Gil, Son, Kane
Monaco 
Stade Brestois 29 
Bordeaux 
Nimes 
Bayern Munich 
FC Augsburg 
Paris Saint Germain 
Toulouse 
CSKA Moscow 
FC Rostov 
Leicester 
Chelsea 
Valencia 
Betis 
Dynamo Kyiv 
Chornomorets Odesa 
Verona 
Inter 
Bayer Leverkusen 
FC Heidenheim 
Borussia Dortmund 
SC Freiburg 
VFL Wolfsburg 
Union Berlin 
Arsenal 
Nottingham Forest 
Everton 
Brentford 
Spartak Moscow 
Lokomotiv Moscow 
Rangers 
Dundee Utd 
Atletico Madrid 
Alaves 
Lens 
Marseille 
Ingulets Petrove 
Shakhtar Donetsk 
AC Milan 
Juventus 
ST Malo 
Manchester City 
Tottenham 
Eintracht Frankfurt 
Werder Bremen 
Girona 
Espanyol 
Feyenoord 
Heerenveen 
ST Etienne 
Montpellier 
Grenoble Foot 38 
Heart Of Midlothian 
Celtic 
Reims 
Lyon 
PSV 
Groningen