While the Red Devils were on the wrong end of a chaotic 4-3 scoreline against Copenhagen on Wednesday, the Hatters earned a respectable point in a 1-1 draw with Liverpool in the top flight last weekend, and here, Sports Mole rounds up all of the latest team news for the two clubs.
MANCHESTER UNITED vs. LUTON TOWN
MANCHESTER UNITED
Out: Casemiro (hamstring), Lisandro Martinez (foot), Luke Shaw (muscle), Amad Diallo (knee), Tyrell Malacia (knee), Jadon Sancho (disciplinary)
Doubtful: Jonny Evans (muscle)
Sports Mole's predicted XI: Onana; Wan-Bissaka, Varane, Maguire, Dalot; McTominay, Eriksen; Pellistri, Fernandes, Rashford; Hojlund
LUTON TOWN
Out: Mads Andersen (thigh), Daniel Potts (ankle), Albert Sambi Lokonga (thigh), Reece Burke (thigh), Jordan Clark (ankle)
Doubtful: Amari'i Bell (thigh)
Sports Mole's predicted XI: Kaminski; Kabore, Mengi, Lockyer, Osho, Doughty; Barkley, Nakamba, Chong; Adebayo, Morris
For data analysis of the most likely results, scorelines and more for this match please click here.