The Red Devils are simply aiming to consolidate second spot in the table, while Liverpool remain rank outsiders for a Champions League place, and here Sports Mole rounds up all of the latest team news for the two clubs.
MANCHESTER UNITED vs. LIVERPOOL
MANCHESTER UNITED
Out: Harry Maguire (ankle), Anthony Martial (knee), Phil Jones (knee), Daniel James (unspecified)
Doubtful: None
Sports Mole's predicted XI: Henderson; Wan-Bissaka, Lindelof, Bailly, Shaw; Fred, McTominay; Rashford, Fernandes, Pogba; Cavani
LIVERPOOL
Out: Virgil van Dijk (knee), Joe Gomez (knee), Joel Matip (ankle), Jordan Henderson (groin), Divock Origi (muscle), Naby Keita (muscle), Ben Davies (muscle), Caoimhin Kelleher (abdominal), Ozan Kabak (muscle), James Milner (unspecified)
Doubtful: None
Sports Mole's predicted XI: Alisson; Alexander-Arnold, Phillips, Williams, Robertson; Fabinho, Thiago, Wijnaldum; Salah, Firmino, Mane
Video prediction
Watch the Sports Mole Football Shorts prediction for this game below: