The Reds defeated Chelsea on penalties in last year's final to get their hands on the trophy, while the visitors have not clinched FA Cup glory since 1960, and here Sports Mole rounds up the team news for both clubs.
LIVERPOOL vs. WOLVERHAMPTON WANDERERS
LIVERPOOL
Out: Virgil van Dijk (hamstring), Diogo Jota (calf), Luis Diaz (knee), Arthur (thigh)
Doubtful: Jordan Henderson (concussion), James Milner (thigh), Roberto Firmino (calf)
Sports Mole's predicted XI: Kelleher; Alexander-Arnold, Matip, Gomez, Robertson; Keita, Fabinho, Henderson; Salah, Nunez, Gakpo
WOLVERHAMPTON WANDERERS
Out: Sasa Kalajdzic (ACL), Boubacar Traore (unspecified), Pedro Neto (ankle), Chiquinho (knee), Daniel Podence (knock)
Doubtful: None
Sports Mole's predicted XI: Sarkic; Semedo, Collins, Kilman, Ait-Nouri; Hodge, Neves, Nunes; Traore, Jimenez, Cunha
For data analysis of the most likely results, scorelines and more for this match please click here.