The Red Devils opened their preparations for the 2022-23 Premier League season with a 4-0 victory over Liverpool in a friendly on Tuesday.
Man United will now continue their pre-season against Melbourne Victory before taking on Crystal Palace and Aston Villa in the same country ahead of returning to Europe for their final two friendlies of the summer.
Ten Hag has made three changes to his starting side for the clash with the A-League Men club, with Tom Heaton replacing David de Gea between the sticks.
De Gea picked up a slight injury in the clash with Liverpool last time out, and the Spain international is not included in the squad for this contest.
There is also no spot in the squad for Raphael Varane, but club captain Harry Maguire has returned, having missed out against Liverpool on Tuesday with a knock that he picked up in training.
Maguire for Varane is the second change from the game against the Reds, while the final alteration sees Anthony Elanga come in for Marcus Rashford, who drops to the bench.
Tyrell Malacia made his debut for the 20-time English champions off the bench against Jurgen Klopp's side, and he is again among the substitutes for the Red Devils here.
Anthony Martial is benefiting from the absence of Cristiano Ronaldo, with the Frenchman again starting through the middle, and he will be looking to add to the goal that he struck against Liverpool.
Jadon Sancho was also on the scoresheet in the team's pre-season opener, with the England international looking to improve on what was an underwhelming first campaign at the club.
Ten Hag made 10 changes at the interval of the clash with Liverpool last time out and that could again be the case in this contest, with the Dutchman keen to make use of his squad.
Hannibal Mejbri, Ethan Laird and Tahith Chong were not used against the Reds, but the trio are again in the squad and will be hoping to be given a chance to impress.
Facundo Pellistri scored Man United's fourth goal against Klopp's side, meanwhile, and he will hoping to have another opportunity to make his mark off the bench here.
MANCHESTER UNITED XI: Heaton; Dalot, Lindelof, Maguire, Shaw; Fred, McTominay; Sancho, Fernandes, Elanga; Martial