Erik ten Hag's men defeated Manchester City 2-1 in Saturday's derby, while the Eagles went down 1-0 to Chelsea in their capital clash, and here Sports Mole rounds up the team news for both clubs.
CRYSTAL PALACE vs. MANCHESTER UNITED
CRYSTAL PALACE
Out: Nathan Ferguson (unspecified), James McArthur (groin)
Doubtful: Joachim Andersen (calf)
Sports Mole's predicted XI: Guaita; Clyne, Tomkins, Guehi, Mitchell; Schlupp, Doucoure, Eze; Olise, Mateta, Zaha
MANCHESTER UNITED
Out: Mason Greenwood (club suspension), Donny van de Beek (knee), Jadon Sancho (fitness), Axel Tuanzebe (unspecified)
Doubtful: Diogo Dalot (hamstring), Marcus Rashford (hip), Anthony Martial (unspecified)
Sports Mole's predicted XI: De Gea; Wan-Bissaka, Varane, Martinez, Shaw; Fred, Casemiro; Antony, Eriksen, Fernandes; Rashford
For data analysis of the most likely results, scorelines and more for this match please click here.