Erik ten Hag's men came out on the wrong end of a 4-3 scoreline in Wednesday's Champions League opener with Bayern Munich, while the Clarets drew 1-1 with Nottingham Forest on Monday night, and here Sports Mole rounds up the team news for both clubs.
BURNLEY vs. MANCHESTER UNITED
BURNLEY
Out: Lyle Foster (suspended), Michael Obafemi (hamstring), Hjalmar Ekdal (knee), Darko Churlinov (blood poisoning)
Doubtful: Vitinho (knee)
Sports Mole's predicted XI: Trafford; Roberts, Al-Dakhil, O'Shea, Taylor; Cullen, Brownhill; Zaroury, Ramsey, Koleosho; Amdouni
MANCHESTER UNITED
Out: Aaron Wan-Bissaka (thigh), Tyrell Malacia (knee), Kobbie Mainoo (ankle), Antony (personal), Amad Diallo (knee), Jadon Sancho (disciplinary), Luke Shaw (unspecified)
Doubtful: Sofyan Amrabat (back), Harry Maguire (muscle), Mason Mount (thigh), Raphael Varane (unspecified)
Sports Mole's predicted XI: Onana; Dalot, Varane, Martinez, Reguilon; Casemiro, McTominay; Garnacho, Fernandes, Rashford; Hojlund
For data analysis of the most likely results, scorelines and more for this match please click here.