The Red Devils struggled for large periods during their 1-0 victory over Canada in their opening match, Martinez making two substitutions at half time in a bid to improve his side's performance.
Thomas Meunier and Amadou Onana were both introduced at that point, and the pair come into the side to replace Leander Dendoncker and Youri Tielemans, with Timothy Castagne seemingly being used in the middle of a back three.
Thorgan Hazard also comes into the team with Yannick Carrasco dropping down to the bench, with Michy Batshuayi retaining his spot in attack.
Meanwhile, Morocco coach Walid Regragui has stuck with the same 11 players which started the goalless draw against Croatia earlier this week.
Noussair Mazraoui had been an injury doubt after needing to be substituted versus the 2018 runners-up, but the left-back has been passed fit to retain his place.
Belgium: Courtois; Alderweireld, Castagne, Vertonghen; Meunier, Witsel, Onana, T.Hazard; De Bruyne, E.Hazard; Batshuayi
Morocco: Bounou; Hakimi, Saiss, Aguerd, Mazraoui; Ounahi, Amrabat, Amallah; Ziyech, En-Nesyri, Boufal
Monaco 
Stade Brestois 29 
Bordeaux 
Nimes 
Bayern Munich 
FC Augsburg 
Paris Saint Germain 
Toulouse 
CSKA Moscow 
FC Rostov 
Leicester 
Chelsea 
Valencia 
Betis 
Dynamo Kyiv 
Chornomorets Odesa 
Verona 
Inter 
Bayer Leverkusen 
FC Heidenheim 
Borussia Dortmund 
SC Freiburg 
VFL Wolfsburg 
Union Berlin 
Arsenal 
Nottingham Forest 
Everton 
Brentford 
Spartak Moscow 
Lokomotiv Moscow 
Rangers 
Dundee Utd 
Atletico Madrid 
Alaves 
Lens 
Marseille 
Ingulets Petrove 
Shakhtar Donetsk 
AC Milan 
Juventus 
ST Malo 
Manchester City 
Tottenham 
Eintracht Frankfurt 
Werder Bremen 
Girona 
Espanyol 
Feyenoord 
Heerenveen 
ST Etienne 
Montpellier 
Grenoble Foot 38 
Heart Of Midlothian 
Celtic 
Reims 
Lyon 
PSV 
Groningen