The Catalan outfit are seven points clear of second-placed Real Madrid at the top of the table, while Valencia occupy 18th, one point from 17th-placed Real Valladolid, and here Sports Mole rounds up the team news.
BARCELONA vs. VALENCIA
BARCELONA
Out: Gavi (suspended), Robert Lewandowski (hamstring), Pedri (hamstring), Ousmane Dembele (hamstring)
Doubtful: None
Sports Mole's predicted XI: Ter Stegen; Araujo, Kounde, Christensen, Alba; F de Jong, Busquets, Kessie; Fati, F Torres, Raphinha
VALENCIA
Out: Gabriel Paulista (leg), Marcos de Sousa (ankle), Jose Gaya (arm), Edinson Cavani (muscle), Nico Gonzalez (foot), Jaume Domenech (knee)
Doubtful: None
Sports Mole's predicted XI: Mamardashvili; Foulquier, Comert, Diakhaby, Lato; Musah, Guillamon, Almeida; Castillejo, Duro, Lino
For data analysis of the most likely results, scorelines and more for this match please click here.