The hosts will enter the match off the back of a 3-1 win over Alaves, while Granada drew 1-1 with Las Palmas last time out, and here Sports Mole rounds up the team news.
BARCELONA vs. GRANADA
BARCELONA
Out: Vitor Roque (suspended), Ferran Torres (thigh), Joao Felix (ankle), Sergi Roberto (Achilles), Alejandro Balde (hamstring), Marcos Alonso (back), Gavi (knee)
Doubtful: Raphinha (thigh), Marc-Andre ter Stegen (back)
Sports Mole's predicted XI: Ter Stegen; Kounde, Araujo, I Martinez, Cancelo; F de Jong, Christensen, Gundogan; Yamal, Lewandowski, Pedri
GRANADA
Out: Kamil Piatkowski (suspended), Gonzalo Villar (suspended), Lucas Boye (thigh), Victor Diaz (knee), Jesus Vallejo (muscle), Raul Fernandez (hamstring)
Doubtful: None
Sports Mole's predicted XI: Batalla; Sanchez, Mendez, Miquel, Maouassa; Pellistri, Melendo, Hongla, Ruiz, Neva; Arezo
For data analysis of the most likely results, scorelines and more for this match please click here.