The Red Devils are currently fifth in the table, one point behind fourth-placed Newcastle United, while Villa sit down in 16th position, and here Sports Mole rounds up the team news.
ASTON VILLA vs. MANCHESTER UNITED
ASTON VILLA
Out: Boubacar Kamara (knee), Ludwig Augustinsson (thigh), Diego Carlos (Achilles)
Doubtful: Emiliano Martinez (head)
Sports Mole's predicted XI: E Martinez; Cash, Konsa, Mings, Digne; Dendoncker, Luiz, McGinn; Watkins, Ings, Bailey
MANCHESTER UNITED
Out: Bruno Fernandes (suspension), Brandon Williams (unspecified), Mason Greenwood (club suspension), Axel Tuanzebe (unspecified), Raphael Varane (hamstring)
Doubtful: Antony (knock), Jadon Sancho (illness), Anthony Martial (back)
Sports Mole's predicted XI: De Gea; Dalot, Lindelof, L Martinez, Shaw; Fred, Casemiro, Eriksen; Antony, Ronaldo, Rashford
For data analysis of the most likely results, scorelines and more for this match please click here.