The Gunners are two points clear of PSV Eindhoven at the top, while Bo Henriksen's men are still in with a chance of pipping Bodo/Glimt to the Europa Conference League spot, and here Sports Mole rounds up the team news for both clubs.
ARSENAL vs. FC ZURICH
ARSENAL
Out: Granit Xhaka (suspended), Mohamed Elneny (hamstring), Emile Smith Rowe (groin)
Doubtful: Bukayo Saka (foot), Matt Turner (groin), Oleksandr Zinchenko (calf)
Sports Mole's predicted XI: Ramsdale; Tomiyasu, Holding, Gabriel, Tierney; Odegaard, Lokonga, Vieira; Nelson, Nketiah, Martinelli
FC ZURICH
Out: Mirlaid Kryeziu (muscle), Ilan Sauter (knock), Blerim Dzemaili (unspecified), Donis Avdijaj (unspecified), Miguel Reichmuth (knock)
Doubtful: Nikola Katic (unspecified)
Sports Mole's predicted XI: Brecher; Mets, Aliti, Kamberi; Boranijasevic, Selnaes, Conde, Guerrero; Marchesano; Okita, Tosin
For data analysis of the most likely results, scorelines and more for this match please click here.