The Gunners have enjoyed a two-week break since losing to Liverpool 2-0 in the FA Cup third round, while Palace suffered a 1-0 defeat to Everton in Wednesday's replay, and here Sports Mole rounds up the team news for both clubs.
ARSENAL vs. CRYSTAL PALACE
ARSENAL
Out: Mohamed Elneny (international), Takehiro Tomiyasu (international), Thomas Partey (thigh), Fabio Vieira (groin), Jurrien Timber (ACL)
Doubtful: Gabriel Jesus (knee), Oleksandr Zinchenko (calf)
Sports Mole's predicted XI: Raya; White, Saliba, Gabriel, Zinchenko; Odegaard, Rice, Havertz; Saka, Jesus, Martinelli
CRYSTAL PALACE
Out: Rob Holding (ankle), Jordan Ayew (international), Michael Olise (thigh), Cheick Doucoure (Achilles), Joel Ward (thigh)
Doubtful: Jesurun Rak-Sakyi (thigh)
Sports Mole's predicted XI: Henderson; Clyne, Andersen, Guehi, Mitchell; Eze, Richards, Lerma, Schlupp; Edouard, Mateta
For data analysis of the most likely results, scorelines and more for this match please click here.