Paulo Bento's men kicked off their quest for a first knockout-stage appearance since 2010 on Wednesday when they played out an uneventful goalless draw with Uruguay.
As for Ghana, they were denied a dream start to their World Cup campaign as they fell to a 3-2 defeat against a star-studded Portugal side in last week's group opener.
Needed a win to get their respective campaigns back on track, Sports Mole takes a look at how the squads of South Korea and Ghana stack up against each other ahead of Monday's contest.
SOUTH KOREA
Most valuable player:
Heung-min Son (£60.4m)
Overall squad value:
£142.4m
Most capped player:
Heung-min Son (105)
Leading goalscorer:
Heung-min Son (35)
Total caps:
936
Total goals:
113
Oldest player:
Kim Tae-hwan (33)
Youngest player:
Lee Kang-in (21)
Average age:
27.8
SQUAD IN FULL
Goalkeepers: Kim Seung-gyu (Al-Shabab), Jo Hyeon-woo (Ulsan Hyundai), Song Bum-keun (Jeonbuk Hyundai Motors)
Defenders: Kim Jin-su (Jeonbuk Hyundai Motors), Hong Chul (Daegu FC), Kim Moon-hwan (Jeonbuk Hyundai Motors), Kim Young-gwon (Ulsan Hyundai), Kwon Kyung-won (Gamba Osaka), Kim Tae-hwan (Ulsan Hyundai), Cho Yu-min (Daejon Hana Citizen), Kim Min-jae (Napoli), Yoon Jong-gyu (FC Seoul)
Midfielders: Jung Woo-young (Al-Sadd), Lee Jae-sung (Mainz), Hwang In-beom (Olympiacos), Na Sang-ho (FC Seoul), Paik Seung-ho (Jeonbuk Hyundai Motors), Kwon Chang-hoon (Gimcheon Sangmu), Paik Seung-ho (Jeonbuk Hyundai Motors), Son Jun-ho (Shandong Taishan), Jeong Woo-yeong (Freiburg), Lee Kang-in (Mallorca), Yang Hyun-jun (Gangwon FC)
Forwards: Son Heung-min (Tottenham), Hwang Ui-jo (Olympiacos), Cho Gue-sung (Jeonbuk Hyundai Motors), Hwang Hee-chan (Wolves)
GHANA
Most valuable player:
Thomas Partey (£32.8m)
Overall squad value:
£187.5
Most capped player:
Andre Ayew (111)
Leading goalscorer:
Andre Ayew (24)
Total caps:
467
Total goals:
70
Oldest player:
Denis Odoi (34)
Youngest player:
Abdul Fatawu Issahaku (18)
Average age:
24.7
SQUAD IN FULL
Goalkeepers: Lawrence Ati-Zigi (St Gallen), Ibrahim Danlad (Asante Kotoko), Abdul Manaf Nurudeen (Eupen)
Defenders: Joseph Aidoo (Celta Vigo), Daniel Amartey (Leicester City), Abdul Rahman Baba (Reading), Alexander Djiku (Racing Strasbourg), Tariq Lamptey (Brighton & Hove Albion), Gideon Mensah (Auxerre), Denis Odoi (Club Bruges), Mohammed Salisu (Southampton), Alidu Seidu (Clermont)
Midfielders: Mohammed Kudus (Ajax), Daniel-Kofi Kyereh (Freiburg), Elisha Owusu (Gent), Thomas Partey (Arsenal), Salis Abdul Samed (Lens)
Forwards: Daniel Afriyie (Hearts of Oak), Andre Ayew (Al Sadd), Jordan Ayew (Crystal Palace), Osman Bukari (Red Star Belgrade), Issahaku Abdul Fatawu (Sporting Lisbon), Antoine Semenyo (Bristol City), Kamal Sowah (Club Bruges), Kamaldeen Sulemana (Rennes), Inaki Williams (Athletic Bilbao)
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